Ictal and postictal semiology in patients with bilateral temporal lobe epilepsy

Logo poskytovatele

Varování

Publikace nespadá pod Pedagogickou fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.
Autoři

ŘEHULKA Pavel DOLEŽALOVÁ Irena JANOUŠOVÁ Eva TOMÁŠEK Martin MARUSIČ Petr BRÁZDIL Milan KUBA Robert

Rok publikování 2014
Druh Článek v odborném periodiku
Časopis / Zdroj EPILEPSY & BEHAVIOR
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www http://ac.els-cdn.com/S1525505014004697/1-s2.0-S1525505014004697-main.pdf?_tid=77ce08ac-9d90-11e4-a779-00000aacb362&acdnat=1421420633_ce85b6b9641f66c12a8efd81cec46dcc
Doi http://dx.doi.org/10.1016/j.yebeh.2014.09.033
Obor Neurologie, neurochirurgie, neurovědy
Klíčová slova Epilepsy; Bitemporal; Bilateral temporal lobe epilepsy; Invasive EEG; Semiology; Postictal unresponsiveness
Popis Bilateral temporal lobe epilepsy is characterized by evidence of seizure onset independently in both temporal lobes. Themain aim of the present study was to determine whether patients with evidence of independent bilateral temporal lobe epilepsy (biTLE) can be identified noninvasively on the basis of seizure semiology analysis. Thirteen patients with biTLE, as defined by invasive EEG, were matched with 13 patients with unilateral temporal lobe epilepsy (uniTLE). In all 26 patients, the frequency of predefined clusters of ictal and periictal signs were evaluated: ictal motor signs (IMSs), periictalmotor signs (PIMSs), periictal vegetative signs (PIVSs), the frequency of early oroalimentary automatisms (EOAs), and the duration of postictal unresponsiveness (PU). Some other noninvasive and clinical data were also evaluated. A lower frequency of IMSs was noted in the group with biTLE (patients = 46.2%, seizures = 20.7%) than in the group with uniTLE (patients = 92.3%, seizures = 61.0%) (p = 0.030; p < 0.001, respectively). The individual IMS average per seizure was significantly lower in the group with biTLE (0.14; range = 0-1.0) than in the group with uniTLE (0.80; range = 0-2.6) (p = 0.003). Postictal unresponsiveness was longer than 5 min in more patients (75.0%) and seizures (42.9%) in the group with biTLE than in the groupwith uniTLE (patients = 30.8%, seizures= 18.6%) (p= 0.047; p= 0.002). The frequency of EOAs, PIMSs, PIVSs, and other clinical data did not differ significantly. There is a lower frequency of ictal motor signs and longer duration of postictal unresponsiveness in patients with biTLE. (C) 2014 Elsevier Inc. All rights reserved.
Související projekty:

Používáte starou verzi internetového prohlížeče. Doporučujeme aktualizovat Váš prohlížeč na nejnovější verzi.