Electrochemical analysis of DNA hexamer d(GCGAGC)
Autoři | |
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Rok publikování | 2016 |
Druh | Článek ve sborníku |
Konference | XVI. Workshop of Physical Chemists and Electrochemists |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Fyzikální chemie a teoretická chemie |
Klíčová slova | DNA hexamer; mercury electrode; pH effect; concentration effect; hairpin |
Popis | The aim of our research is the voltammetric analysis of the DNA hexameric mini-hairpin d(GCGAGC). The cyclic voltammetric experiment on a hanging mercury drop electrode (HMDE) yields reduction signals of adenine (A) and cytosine (C) moieties and two oxidation signals of guanine moieties (G); these signals were investigated with respect to the hexamer concentration and pH of buffered solutions (phosphate-acetate buffer). Although the character of LSV curves is similar for different concentrations and pHs, the elimination voltammograms are different and show the other character of adsorption. |
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