Structure-functional study of lectins: key players in a fight between host and pathogen

• Autoři: HOUSER Josef; MALINOVSKÁ Lenka; FUJDIAROVÁ Eva; JANČAŘÍKOVÁ Gita; KOMÁREK Jan; HOLKOVÁ Jitka; WIMMEROVÁ Michaela
• Rok publikování: 2019
• Druh: Konferenční abstrakty
• Fakulta / Pracoviště MU: Středoevropský technologický institut
• Popis: Lectins are proteins that reversibly interact with sugars. They role range from glycoprotein folding, through cell maturation to host-pathogen recognition. To describe a lectin we apply a broad range of biophysical techniques. In addition to analysis of its affinity and specificity, we also determine lectin structures and combine our findings with in silico modelling. Our results may find application in basic research, medicine as well as biotechnologies.

Související projekty

• Czech Infrastructure for Integrative Structural Biology
• CEITEC 2020
• CIISB - Česká infrastruktura pro integrativní strukturní biologii pro lidské zdraví