Current treatment of behavioral and cognitive symptoms of Parkinson's disease

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Publikace nespadá pod Pedagogickou fakultu, ale pod Středoevropský technologický institut. Oficiální stránka publikace je na webu muni.cz.
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REKTOROVÁ Irena

Rok publikování 2019
Druh Článek v odborném periodiku
Časopis / Zdroj Parkinsonism and Related Disorders
Fakulta / Pracoviště MU

Středoevropský technologický institut

Citace
www https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(19)30087-2
Doi http://dx.doi.org/10.1016/j.parkreldis.2019.02.042
Klíčová slova Apathy; Behavioral; Cognitive; Dementia; Dopaminergic; Impulse control disorders; Mild cognitive impairment; Parkinson's disease; Psychosis; treatment
Přiložené soubory
Popis Cognitive and behavioral symptoms are common in Parkinson's disease, may occur even in the prodromal stages of the disease, worsen with disease progression, and surpass motor symptoms as the major factors affecting patient quality of life and caregiver burden. The symptoms may be caused by the disease pathology or they may represent adverse effects of treatment, or both etiological factors may contribute. Although many of these symptoms are related to dopaminergic dysfunction or dopaminergic medication, other neurotransmitters are involved as well. Behavioral symptoms including impulse control disorders, apathy, psychosis, as well as mild cognitive impairment and dementia are reviewed with a special focus on current treatment approaches.
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