SCHIFF BASES AS POTENTIAL THERAPEUTIC AGENTS

Varování

Publikace nespadá pod Pedagogickou fakultu, ale pod Farmaceutickou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	BALLAYOVÁ Veronika KAUEROVÁ Tereza KOLLÁR Peter FARSA Oldřich
Rok publikování	2023
Druh	Další prezentace na konferencích
Fakulta / Pracoviště MU	Farmaceutická fakulta
Citace
Popis	Schiff bases, which are carrying imine or azomethine functional group, are versatile pharmacophores capable of forming chelating complexes with various metals. Metal complexes play a crucial role in pharmaceutical sciences due to their wide and significant activities.1 Synthesized basic thiosemicarbazone and semicarbazone derivatives of acetophenone may be bioactive compounds as well. Through three-step synthesis it is possible to obtain three arene substitution isomers of basic thiosemicarbazone and semicarbazone derivatives of acetophenone.
Související projekty:	Interní grantová agentura Masarykovy univerzity Návrh, syntéza a hodnocení derivátů skupin léčiv s inhibiční enzymatickou aktivitou Basic ketones and their derivatives as potential anti-infective and anti-tumor drugs