Koincidence diabetes mellitus 1. typu a roztroušené sklerózy - kazuistika

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Title in English	Co-Occurrence of Type 1 Diabetes Mellitus and Multiple Sclerosis - a Case Report
Authors	ŠROTOVÁ Iva PRAKSOVÁ Petra VLČKOVÁ Eva KEŘKOVSKÝ Miloš BENEŠOVÁ Yvonne ŠTOURAČ Pavel BEDNAŘÍK Josef
Year of publication	2013
Type	Article in Periodical
Magazine / Source	Ceska a slovenska neurologie a neurochirurgie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Neurology, neurosurgery, neurosciences
Keywords	multiple sclerosis; type 1 diabetes mellitus; interferon beta-1a
Attached files	EL_Okacova_Srotova_.pdf
Description	Type 1 diabetes mellitus (DM1) and multiple sclerosis (MS) are organ-specific autoimmune diseases. DM1 and MS carry a number of common features, especially disturbed autotolerance and regulation of the immune system. In our case report, we present a patient who was diagnosed with DM1 with multiple organ involvement at the age of 15. At the age of 31, we diagnosed CIS (Clinically Isolated Syndrome) and started treatment with subcutaneous interferon beta-1a (Rebif 44). The purpose of this report is to emphasize possible coincidence of DM1 and MS, common features of both autoimmune diseases and possible pitfalls of the diagnostic process.