PRES (Posterior reversible encefalopathy syndrome) doprovázející preeklampsii u ženy s dvoj četným těhotenstvím - kazuistika

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Title in English PRES (Posterior reversible encefalopathy syndrome) in a pre-eclamptic woman with twin pregnancy - case report
Authors

JURA R. ŠROTOVÁ Iva ADAMOVÁ Blanka ŠPRLÁKOVÁ-PUKOVÁ Andrea JANKŮ Petr BEDNAŘÍK Josef

Year of publication 2015
Type Article in Periodical
Magazine / Source Anesteziologie & intenzivní medicína
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords Posterior reversible encefalopathy syndrom (PRES); pregnancy; pre-eclampsia; cortical blindness
Description Posterior reversible encefalopathy syndrome (PRES) is a serious neurological condition with varied clinical manifestation. It is rare during pregnancy. We present a case of PRES in a 35-year-old female immediately after the delivery of twins by Caesarean section. The patient fully recovered. A 35-year-old primigravida with twin pregnancy underwent a Caesarean section at 35 weeks of gestation because of pregnancy-induced preeclampsia (hypertension, proteinuria, bilateral pedal oedema). Approximately 20 hours after the Caesarean section there was a rapid decline of visual acuity. We clinically diagnosed cortical blindness. A computed tomography (CT) scan of the brain showed bilateral occipital hypodensity, CT angiogram showed no pathological findings. The patient was immediately transferred to the neurological Intensive Care Unit (ICU). Magnetic resonance showed hyperintensity (T2W2) in the occipital lobes and the cerebral trunk. After the delivery patient had been normoten-sive. Subsequently after the development of the neurological symptoms, the patient's blood pressure increased to 200/110 mm Hg. PRES was diagnosed on the basis of the clinical presentation and the radiological reports and the patient was promptly treated with intravenous antihypertensives and magnesium sulphate. The visual impairment subsided within 24 hours without a relapse and the clinical neurological examination was normal. The patient was discharged in one week with normal blood pressure on oral antihypertensive medication. Pre-eclampsia is a predisposing factor for PRES in pregnancy. We report a case of uncommon post-partum PRES presentation and focus on the importance of early diagnosis and optimal critical care management.

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