Redox-Pair-Defined Electrochemical Measurements: Biamperometric Setup for Elimination of Interferent Effects and for Sensing of Unstable Redox Systems
| Authors | |
|---|---|
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | ChemElectroChem |
| MU Faculty or unit | |
| Citation | |
| web | http://onlinelibrary.wiley.com/doi/10.1002/celc.201600076/full |
| Doi | http://dx.doi.org/10.1002/celc.201600076 |
| Field | Physical chemistry and theoretical chemistry |
| Keywords | analytical methods; cyclic biamperometry; electrochemistry; redox chemistry; sensors |
| Description | Routine, large-scale monitoring, such as point-of-care systems, requires inexpensive and simple analytical schemes. An electroanalytical concept of biamperometry for such sensing systems has been overlooked due to widespread potentiostat-controlled experiments. Herein, biamperometry is introduced as a powerful tool. In particular, its ability to eliminate electrochemical interference is highlighted for a case study on employing [Fe(CN)(6)](4-)/[Fe(CN)(6)](3-), aminoferrocene (Fe2+)/[Ru(NH3)(6)](3+), and ascorbic acid as two redox pairs and one interfering compound, respectively. A specific signal 15 times higher than that of an unspecific signal is observed, even under unfavorable conditions such as a 1:5 molar ratio of specific-to-interfering redox entities. This system is successfully used to determine glucose in blood plasma. A further promising usage of biamperometry is illustrated by the study of an unstable redox system: the oxygen-dependent oxidation of [Ru(NH3)(6)](2+) in an aqueous environment. |
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