Diversity of MHC IIB genes and parasitism in hybrids of evolutionarily divergent cyprinoid species indicate heterosis advantage

• Authors: ŠIMKOVÁ Andrea; GETTOVÁ Lenka; CIVÁŇOVÁ Kristína; SEIFERTOVÁ Mária; JANÁČ Michal; VETEŠNÍK Lukáš
• Year of publication: 2021
• Type: Article in Periodical
• Magazine / Source: Scientific reports
• MU Faculty or unit: Faculty of Science
• Web: https://doi.org/10.1038/s41598-021-96205-x
• Doi: http://dx.doi.org/10.1038/s41598-021-96205-x
• Keywords: MHC IIB genes; heterosis advantage; cyprinid fish
• Description: The genes of the major histocompatibility complex (MHC) are an essential component of the vertebrate immune system and MHC genotypes may determine individual susceptibility to parasite infection. In the wild, selection that favors MHC variability can create situations in which interspecies hybrids experience a survival advantage. We assessed MHC IIB genetic variability and its potential relationships to hosts' ectoparasite communities.

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