Polymorphous low-grade neuroepithelial tumor of the young

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Authors

HENDRYCH Michal HEMZA Jan KOČVAROVÁ Jitka PEŠLOVÁ Eva SOCHŮRKOVÁ Daniela DOLEŽALOVÁ Irena BRICHTOVÁ Eva PAIL Martin BRÁZDIL Milan JANČÁLEK Radim VANÍČEK Jiří HERMANOVÁ Markéta

Year of publication 2021
Type Article in Periodical
Magazine / Source Česká a slovenská neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2021-3-9/polymorphous-low-grade-neuroepithelial-tumor-of-the-young-127783
Doi http://dx.doi.org/10.48095/cccsnn2021282
Keywords Polymorphous low-grade neuroepithelial tumor of the young
Description Hereby we would like to present a case report of a 27-year-old male patient with drug- -resistant structural epilepsy based on the diagnosis of the polymorphous low-grade neuroepithelial tumor of the young (PLNTY), first reported by Huse et al in 2017 [1]. PLNTY is a sporadic epileptogenic tumor characterized by an oligodendroglial-like component, diffuse CD34 expression, and alteration of the mitogen-activated protein (MAP) kinase signaling pathway. It shares multiple characteristics with other diffuse low-grade gliomas, especially with oligodendroglioma; nevertheless, its distinction is crucial because of the favorable prognosis of PLNTY.
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