CCL2/MCP-1, interleukin-8, and fractalkine/CXC3CL1: Potential biomarkers of epileptogenesis and pharmacoresistance in childhood epilepsy

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Authors	ČESKÁ Katarína PAPEŽ Jan OŠLEJŠKOVÁ Hana SLABÝ Ondřej RADOVÁ Lenka LOJA Tomáš LIBÁ zuzana SVĚRÁKOVÁ Anna BRÁZDIL Milan AULICKÁ Štefánia
Year of publication	2023
Type	Article in Periodical
Magazine / Source	EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
MU Faculty or unit	Faculty of Medicine
Citation
web	https://www.sciencedirect.com/science/article/pii/S1090379823000910?via%3Dihub
Doi	http://dx.doi.org/10.1016/j.ejpn.2023.06.001
Keywords	Chemokine; Cytokine; Epileptogenesis; Interleukin; Pharmacodependent; Pharmacoresistant.
Attached files	CCL2_MCP-1__interleukin-8__and_fractalkine_CXC3CL1_Potential_biomarkers_of_epileptogenesis_and_pharmacoresistance_in_childhood_epilepsy.pdf
Description	Confirmation of the theory that IL-8 is generated from glial cells or astrocytes, not by leakage from plasma. • New insights into processes of epileptogenesis and development of pharmacoresistance in epilepsy with potential impact on developing disease-modifying drugs in epilepsy.
Related projects:	Transcriptomics and DNA methylation analysis in patients with focal cortical dysplasia Národní ústav pro neurologický výzkum