Bacteriophages: an alternative or a powerful complement to antibiotics?

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Authors

KUČEROVÁ Eliška BOTKA Tibor MAŠLAŇOVÁ Ivana KUNTOVÁ Lucie FINSTRLOVÁ Adéla DOŠKAŘ Jiří PANTŮČEK Roman

Year of publication 2023
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
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Description Bacterial viruses, or bacteriophages, are the most abundant entity in the world and form an everyday part of our lives. However, despite more than one hundred years of human interest in using them to fight bacterial infections, their interactions with the bacterial host and the implications of these interactions considering the treatment are still poorly understood. Even so, phages are either regularly used in some Eastern countries to treat bacterial infections or offered as an experimental treatment where antibiotics are failing today (Poland, USA, Australia, etc.)1. Also, pilot clinical trials further confirm that side or negative effects on patients’ health during treatment are none or minimal, especially when compared to antibiotic treatment. Unfortunately, it is impossible to skip antibiotics or other treatments entirely, so it is also essential to be aware of the interactions of bacteriophages with other drugs, primarily antibiotics.
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