Influence of pretreatment with immunosuppressants on O-demethylation of dextromethorphan in isolated perfused rat liver.

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Authors

HADAŠOVÁ Eva CHARVÁTOVÁ Zuzana NERUŠILOVÁ Kateřina HYKSOVÁ Marie ZELENKOVÁ Olga

Year of publication 1999
Type Article in Periodical
Magazine / Source Exp. Toxic. Pathol.
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords liver - rat - immunosuppression - cytochrome P450 2D
Description The study describes the influence of substances with immunosuppressive properties - cyclophosphamide, cycloheximide and dexamethazone on the activity of cytochrome P 450 2D1 in the rat liver.
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