Okrelizumab v rozdílných indikacích

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Title in English	Okrelizumab in different indications
Authors	ŠROTOVÁ Iva HLADÍKOVÁ Magdaléna KOLČAVA Jan ŠTOURAČ Pavel PETRÁŠOVÁ Martina
Year of publication	2023
Type	Article in Periodical
Magazine / Source	Multiple sclerosis News
MU Faculty or unit	Faculty of Medicine
Citation
web	https://www.worldmednet.cz/okrelizumab-v-rozdilnych-indikacich/
Keywords	Okrelizumab; multiple sclerosis
Description	Multiple sclerosis (MS) is a chronic, immune-mediated neurological disease of the central nervous system. The inflammatory process and inflammation-triggered neurodegeneration play an important role in the pathogenesis of the disease. B-lymphocytes are thought to be the key factors responsible for tissue involvement. In recent years, attention has therefore focused on the development of anti-CD20 monoclonal antibodies that selectively deplete B-cells.