Perspektivy použití monoklonálních protilátek v protinádorové imunoterapii

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Title in English Perspectives of monoclonal antibodies in anti-cancer therapy
Authors

ŽALOUDÍK Jan

Year of publication 2000
Type Chapter of a book
MU Faculty or unit

Faculty of Medicine

Citation
Description Critical evaluation of the impact of passive anti-cancer immunotherapy with monoclonal antibodies with special concern to the limitations as heterogeneity of expression target antigens within the tumor, immune tolerance of the tumor and disproportionality between the tumor infiltrating effector cells and cancer cell within the tumor bulk. Possible contribution of monoclonal antibody therapy is estimated for real situations in clinical oncology.
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