Palmatine and Berberine Isolation Artifacts
| Authors | |
|---|---|
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Natural Products |
| MU Faculty or unit | |
| Citation | |
| Web | DOI: 10.1021/np0204996 |
| Doi | http://dx.doi.org/10.1021/np0204996 |
| Field | Organic chemistry |
| Keywords | alkaloid; isoquinoline; palmatine; berberine; NMR; X-ray; artifact |
| Description | Some 8-substituted derivatives of the protoberberine alkaloids palmatine and berberine have been prepared and investigated by 1D and 2D NMR spectroscopy (H-1, C-13, N-15). Complete NMR data for the 8-hydroxy-, 8-methoxy-, 8-ethoxy-, and 8-trichloromethyl-7,8-dihydro derivatives of palmatine and berberine, as well as X-ray data for 8-methoxydihydroberberine, 8-trichloromethyldihydropalmatine, and 8-trichloromethyldihydroberberine are presented. The physicochemical data for all of these compounds are reviewed and compared with previously published values. |
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