Fuzzification, weight and summation of risk factors in a patient improves the prediction of risk for cardiac death.

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Authors

HONZÍK Petr HRABEC Jakub LÁBROVÁ Ruzena SEMRÁD Borivoj HONZÍKOVÁ Nataša

Year of publication 2003
Type Article in Periodical
Magazine / Source Scripta Medica
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords Myocardial infarction; cardiac death; risk stratification; fuzzy method; weighted method.
Description Patients surviving myocardial infarction are at risk of cardiac death. The predictive value of non-invasive indices of risk (ejection fraction<40%, positive late potentials, a frequency of ventricular premature complexes>10/hour, baroreflex sensitivity<3ms/mmHg or low heart rate variability, SDNN index<30ms, SDANN<50 ms) is insufficient. New fuzzy and weighted methods for the stratification of patients at risk, which take into account that the borderline between a risky and non-risky value of a risk factor is not sharp, and significance of factors, were developed. New individual risk factors based on summation of fuzzified risk factors (Fuzzy Sum r.f., Fuzzy-Weighted Sum r.f.) were introduced. By this method, sensitivity 40 and specificity 97% were reached at positive predictive value 50%.
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