Structures of the lectins from Pseudomonas aeruginosa: Insights into molecular basis for host glycan recognition
| Authors | |
|---|---|
| Year of publication | 2004 |
| Type | Article in Periodical |
| Magazine / Source | Microbes and Infection |
| MU Faculty or unit | |
| Citation | |
| Field | Biochemistry |
| Keywords | lectin; Pseudomonas aeruginosa; cystic fibrosis; crystal structure |
| Description | The opportunistic human pathogen Pseudomonas aeruginosa produces two lectins in close association with virulence factors: PA-IL and PA-IIL, which bind to galactose- and fucose/mannose-containing glycoconjugates, respectively. We review here the structural aspects of these lectins are related to their putative roles in host recognition, cell surface adhesion and biofilm formation. |
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