Specifická baktericidní agens v některých nových rodech čeledi Enterobacteriaceae
| Title in English | Specific bacteriocins in some new genera of the family Enterobacteriaceae |
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| Authors | |
| Year of publication | 2004 |
| MU Faculty or unit | |
| Description | For this research, we obtained sets (at least 50 strains each) of the genera: Leclercia, Kluyvera, Citrobacter and Enterobacter, just as scanty sets (5-9 strains each) of the genera: Providencia, Budvicia and Pragia, from the Reference Laboratory for E. coli and Shigellae of the National Institute of Public Health in Prague. In all the sets, a careful screening was accomplished to detect a production of inhibitory agents into growth medium: of bacteriophages, corpuscular and molecular bacteriocins, microcins and siderophores. A numerical survey af all findings is stated in the table in the part ZC of this report. All the inhibitory agents found were closely investigated by accessible analytical methods of microbiology and molecular biology. This investigation brought new aspects of the general knowledge on them. The most important general conclusions of our research may be shortly summarized as follows. Taxons of the family Enterobacteriaceae differ from each other significantly by the incidence of lysogenic and bacteriocinogenic strains, just as though less explicitly of strains producing siderophores. Any taxon with a higher incidence of lysogenic strains displays as a rule a lower incidence of bacteriocinogenic ones and vice versa. Also, taxons with a higher incidence of strains producing corpuscular bacteriocins usually do not produce molecular bacteriocins and vice versa. Inhibitory agents requiring specific cellular receptors for their specific effects, show activity spectra usually limited to strains of their own genera. |
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