Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce

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Title in English Nucleotide polytmorphisms in genomes of closely related treponemes and their detection
Authors

MATĚJKOVÁ Petra ŠMAJS David

Year of publication 2004
Type Article in Proceedings
Conference Sborník abstraktů XIII. konference mladých mikrobiologů Tomáškovy dny 2004
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords T. pallidum; DNA microarray technology
Description When comparing genomes of T. pallidum subspecies, no extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). Anotace anglicky: No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts).
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