Preparation of 1-Adamantylketones: Structure, Mechanism of Formation and Biological Activity of Potential Byproducts
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Collection of Czechoslovak Chemical Communications |
| MU Faculty or unit | |
| Citation | |
| Field | Organic chemistry |
| Keywords | Collect. Czech. Chem. Commun. 2006; 71(5); 709-722. |
| Description | Reactions between adamantane-1-carbonyl chloride and several Grignard reagents as well as interactions with solvents have been examined. Some new and unexpected adamantane derivatives were isolated, fully characterized and their biological activity determined. In particular, an unexpected isochromanone 16 was formed in an SEAr process where a stable hydrocarbon was the leaving group. |
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