Klinický materiál pro průkaz syfilis metodou polymerázové řetězové reakce.

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Title in English Clinical specimens for PCR detection of syphilis
Authors

WOZNICOVÁ Vladana VOTAVA Miroslav FLASAROVÁ Magdalena

Year of publication 2007
Type Article in Periodical
Magazine / Source Epidemiologie, mikrobiologie, imunologie.
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords syphilis; PCR; clinical samples
Description A review is presented of types of clinical specimens used for diagnosis of syphilis by polymerase chain reaction. PCR is a routine method for detection of T. pallidum in swabs of chancres and primary and secondary syphilis mucocutaneous lesions. Whole blood, cerebrospinal fluid, amniotic fluid, aspirate and biopsy specimens, and paraffin-embedded tissues can also be tested by PCR for T. pallidum. However, further research on PCR detection sensitivity at various stages of syphilis is needed before these specimens are used in clinical practice.
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