Correlation of Expression of Ki-67, EGFR, c-erbB-2,MMP-9, p53, bcl-2, CD34 and Cell Cycle Analysis with Survival in Head and Neck Squamous Cell Cancer

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Authors

SMILEK Pavel DUŠEK Ladislav VESELÝ Karel ROTTENBERG Jan KOSTŘICA Rom

Year of publication 2006
Type Article in Periodical
Magazine / Source Journal of Experimental & Clinical Cancer Research
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords Head and neck cancer; mitotic index;bcl-2;DNA cytometry
Description The analysis of the set of 217 patients suffering from head and neck carcinoma was done. Cytokinetic parameters strongly correlated with grade score.Positivity in bcl-2, and MMP-9 was related to OS. Positivity of EGFR, C-erbB-2, CD34, p53 did not reached statistically significant value in association to EFS or OS.
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