Microwave - Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines

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Authors

NEUSCHL Michal BOGDAL Darek POTÁČEK Milan

Year of publication 2007
Type Article in Periodical
Magazine / Source Molecules
MU Faculty or unit

Faculty of Science

Citation
Field Organic chemistry
Keywords Azomethine ylide; intramolecular 1/3-dipolar cycloaddition; microwave - assisted synthesis; hexahydro-1H-pyrrolo[3/2-c]quinoline
Description New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated.
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