Ovlivnění exprese mRNA genu SMN2 inhibitory histonových deacetyláz a jejich vliv na fenotyp spinální svalové atrofie I. a II. typu

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Title in English Regulation of mRNA expression of the SMN2 gene by histone deacetylase inhibitors and their influence on the phenotype of type I and II spinal muscular atrophy
Authors

VONDRÁČEK Petr ZAPLETALOVÁ Eva OŠLEJŠKOVÁ Hana MLČÁKOVÁ Lenka FAJKUSOVÁ Lenka

Year of publication 2007
Type Article in Periodical
Magazine / Source Česká a Slovenská Neurologie a Neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords spinal muscular atrophy; SMN (survival motor neuron) gene; histone deacetylase inhibitors; phenylbutyrate; valproic acid; Hammersmith scale
Description Regulation of mRNA expression of the SMN2 gene by histone deacetylase inhibitors and their influence on the phenotype of type I and II spinal muscular atrophy

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