Anxiolytické/antidepresivní účinky kanabinoidu kanabidiolu a kanabinoidního antagonisty rimonabantu ve 2 zvířecích modelech

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Title in English	Anxiolytic/antidepressant-like effects of cannabidiol and rimonabant in two animal models
Authors	PISTOVČÁKOVÁ Jana ŠULCOVÁ Alexandra
Year of publication	2008
Type	Article in Periodical
Magazine / Source	Psychiatrie, časopis pro moderní psychiatrii
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	cannabinoid; olfactory bulbectomy; social defeat; mice
Description	Behavioural and immune effects of cannabidiol and rimonabant were studied in the model of bilateral olfactory bulbectomy in rodents and the behavioural effects of both drugs were studied in the social defeat mice mode. These results were compared with data obtained with clinically effective antidepressants and axiolytics.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.