Do the female hormones and repeated administration of methamphetamine affect the spontaneous i.v. self-administration of the drug in rats?

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Authors

KUČEROVÁ Jana VRŠKOVÁ Dagmar ŠULCOVÁ Alexandra

Year of publication 2008
Type Article in Periodical
Magazine / Source Prague medical report : interdisciplinary biomedical journal of the First Faculty of Medicine, Charles University in Prague.
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords behavioural sensitization; i.v. self-administration; estrogen; rat
Description The model of i.v. self-administration of MET (or saline as control) combined with fourteen days (14 D) of intermittent pretreatment with MET (or saline) was used hypothesizing potential influence of behavioral sensitization to MET on the spontaneous intake in twenty-one i.v. self-administration everyday sessions (120 min.) in male and female ovariectomized rats with and without estrogen substitution.
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