Combined 3-in-1 photometric, fluorimetric and contactless conductometric on-capillary detector for capillary separations: Applicability for simultaneous detection in CE

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Authors	RYVOLOVÁ Markéta PREISLER Jan KRÁSENSKÝ Pavel FORET František HAUSER Peter PAULL Brett MACKA Miroslav
Year of publication	2008
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	A new design of on-capillary detection combining 3 detection modes - photometric (PD), fluorimetric (FD) and contactless conductivity (C4D) - in one identical point of detection has been recently introduced, tested and characterised. This design allows a combined 3-in-1 detection in capillary separation techniques (CE, CEC, capillary- and nano-LC). A key advantage is the concurrent availability of the three independent on-column detection techniques in the same point, thus avoiding undesirable shifts in separation times caused by multiple parallel detectors. The per-definition concurrent availability of all the 3 detection modes (PD, FD, C4D) offers another unique advantage for the analysis of complex samples, where each of the single detection modes alone might yield an incomplete detection of the present analytes.
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