Léčba atypickými antipsychotiky a jejich volba podle spektra nežádoucích účinků

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Title in English Treatment with atypical antipsychotic drugs and their selection based on the spectrum of side effects
Authors

PŘIKRYL Radovan

Year of publication 2009
Type Article in Periodical
Magazine / Source Psychiatrie pro Praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords antipsychotics; diabetes; dyslipidaemia; weight; metabolic syndrome; prolactin
Description The introduction of second-generation antipsychotics into clinical practice has significantly improved the treatment of schizophrenia. When selecting a particular drug, however, its side-effect profile has to be considered in addition to affecting the targeted symptoms. The main side effects of first-generation antipsychotics include extrapyramidal side effects and hyperprolactinaemia which, along with obesity, hyperglycaemia, hyperlipidaemia, or cardiac complications, are considered to be the major risks associated with the treatment with second-generation antipsychotics. The physician must carefully assess the benefit as well as possible risks related to the side effects of the antipsychotic selected. The selection of a suitable antipsychotic must therefore be strictly individual, taking into account the benefit on the one hand and the possible risks on the other.
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