Inaccuracy In Subject's Behavioral Response - Impact On Analysis Of Functional Magnetic Resonance Imaging Data

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Authors	MIKL Michal DRASTICH Aleš HLUŠTÍK Petr MAREČEK Radek BRÁZDIL Milan
Year of publication	2008
Type	Article in Proceedings
Conference	19-TH BIENAL INTERNATIONAL EURASIP CONFERENCE BIOSIGNAL 2008 BOOK OF ABSTRACTS
MU Faculty or unit	Faculty of Medicine
Citation
Field	Neurology, neurosurgery, neurosciences
Keywords	fMRI; inaccuracy; behavioral response; analysis
Description	The aim of this work is to find how much the fMRI results depend on inaccuracy in subject's behavioral response. We found covariance between specific columns of design and differential (inaccuracy) matrix is a good measure of inaccuracy. Estimated effect size as well as t-statistics for higher level of noise depend linearly on this covariance. The results from theoretical relationships and simulations with synthetic data were verified with real data. Our findings contribute to better understanding of problem of inaccuracy in subject's behavioural response.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.