Novinky v diagnostice a léčbě neuroblastomu.

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Title in English Advances in neuroblastoma diagnostics and treatment.
Authors

MAZÁNEK Pavel BAJČIOVÁ Viera ŠTĚRBA Jaroslav KUGLÍK Petr VESELSKÁ Renata

Year of publication 2008
Type Article in Periodical
Magazine / Source Onkológia
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.solen.sk
Field Oncology and hematology
Keywords neuroblastoma pediatric oncology new terapie antiangiogenic therapy metronomic chemotherapy COMBAT genetics of childhood cancer
Description Neruoblastoma is the most common extracranial solid tumor of a childhood. Neuroblastoma is well known for ist variability in clinical behavioral and distinct biological features. In a history of pediatric oncology it is a first disease, where the biological marker ( NMYC amplification) was used for a prospective therapeutical randomisation. Current research is focused on detection of a new biological prognostic markers in neuroblstoma and implementation af a new therapeutical apporoaches into a clinical practise ( eg. antiangiogenic therapies, metronomic chemotherapy, biotherapy, immunotherapy.)
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