Haplotype analysis of TLR2 and TLR9 gene polymorphisms in Czech patients with chronic periodontitis

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Authors	IZAKOVIČOVÁ HOLLÁ Lydie VOKURKA Jan HRDLIČKOVÁ Barbara AUGUSTÍN Peter FASSMANN Antonín
Year of publication	2009
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	The aim of this study was to study selected polymorphisms in the TLR genes and their association with the development and/or progression of chronic periodontitis (CP). In conclusion, although we did not find a significant role of TLR2 gene in CP, our results indicate that the three polymorphisms in the TLR9 gene act in a cooperative fashion and may be associated with a susceptibility to CP at least in our population.
Related projects:	Dental research centre Analýza polymorfizmů v genech prozánětlivých a remodelačních faktorů ve vztahu k imunitní reakci a klinickému stavu pacientů s parodontitidou