Bilateral changes of cannabinoid receptor type 2 in the dorsal root ganglia of different rat neuropathic pain models

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Authors	HRADILOVÁ SVÍŽENSKÁ Ivana KLUSÁKOVÁ Ilona BRÁZDA Václav DUBOVÝ Petr
Year of publication	2009
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Immunohistochemistry and in situ hybridization has shown that CB2 is present both in the DRG neurons and satellite cells after unilateral nerve damage to a peripheral nerve. However the signal was higher ipsilaterally then contralaterally. The changes in CBR2 synthesis and distribution in the DRG cells could play important role in sensitivity of the damaged nerve.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.