Bilateral changes of cannabinoid receptor type 2 in the dorsal root ganglia of different rat neuropathic pain models

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Authors

HRADILOVÁ SVÍŽENSKÁ Ivana KLUSÁKOVÁ Ilona BRÁZDA Václav DUBOVÝ Petr

Year of publication 2009
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Immunohistochemistry and in situ hybridization has shown that CB2 is present both in the DRG neurons and satellite cells after unilateral nerve damage to a peripheral nerve. However the signal was higher ipsilaterally then contralaterally. The changes in CBR2 synthesis and distribution in the DRG cells could play important role in sensitivity of the damaged nerve.
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