Separation of Attogram Terpenes by CZE with Fluorometric Detection

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Authors

KUBESOVÁ Anna HORKÁ Marie RŮŽIČKA Filip ŠLAIS Karel GLATZ Zdeněk

Year of publication 2010
Type Article in Periodical
Magazine / Source Journal of Chromatography A
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TG8-5120K3X-2&_user=989393&_coverDate=11%2F12%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000049911&_version=1&_urlVersion=0&_userid=989393&md5=562ae523
Doi http://dx.doi.org/10.1016/j.chroma.2010.09.038
Field Analytic chemistry
Keywords Capillary electrophoresis; Fluorometric detection; Poly(ethylene glycol)4-(1-pyrene)-butanoate; Terpenes; Farnesol; Candida albicans
Description Farnesol, is produced by Candida albicans as an extracellular quorum-sensing molecule that influences expresion of a number of virulence factors, especially morphogensis and biofilm formation. It enables this yeast to cause serious nosocomial infections. The sensitivity of this method was demonstrated on the separation of farnesol directly from the cultivation medium.
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