Repetitive transcranial magnetic stimulation and treatment of negative symptoms of schizophrenia

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Authors

PŘIKRYL Radovan

Year of publication 2011
Type Article in Periodical
Magazine / Source Neuroendocrinology Letters
MU Faculty or unit

Central European Institute of Technology

Citation
Field Psychiatry, sexuology
Keywords negative symptoms; repetitive transcranial magnetic stimulation; rTMS; schizophrenia; treatment
Description One of the fundamental prerequisites of the successful schizophrenia treatment is represented by an adequately significant impact on the negative symptoms of schizophrenia. Since the present pharmacotherapy has probably reached its limit in this area, there is a logical effort to utilize other, non-pharmacological methods. One of the most promising supplements that has been for a long time verified in the clinical practice is rTMS. Most of the studies have arrived at the conclusion that rTMS is an efficient method in the treatment of negative symptoms of schizophrenia. A valuable contribution to the assessment of the rTMS application in the treatment of negative symptoms is represented by meta-analyses. The metaanalyses indicate that the effect is mild to moderate (d=0.43 to 0.68). To sum it up, there will be higher probability of the rTMS effect on negative symptoms if 10 Hz stimulating frequency and a longer stimulation period in the extent at least three, ideally four to six weeks is used.
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