Nanofibrous scaffolds for tissue engineering

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Authors

PAVLIŇÁK David ŠVACHOVÁ Veronika KEDROŇOVÁ Eva ALBERTI Milan HYRŠL Pavel DUŠKOVÁ Monika NEJEZCHLEBOVÁ Helena VOJTEK Libor

Year of publication 2011
Type Article in Proceedings
Conference Potencial and Applications of Surface Nanotreatment of Polymers and Glass
MU Faculty or unit

Faculty of Science

Citation
Keywords tissue engineering;nanomaterial;nanotechnology;electrospinning;plasma-chemical treatment;bactericidal efect;bioactivity;chemical luminiscence
Description Tissue engineering aims to develop biologically functional scafolds for the repair, replacement, or regeneration of damaged tissues. The aim of this work was to find a new manufacturing process of a biologically functional scaffolds. Various synthetic biopolymers, like a gelatine, PVA, collagen have been electrospun to satisfy different clinical requirments. The main research idea was to develop a suitable bactericidal agent that could be sufficiently biocompatible and biodegradable. These requirements fulfilled an oxycellulose which was produced using plasma-chemical reaction. Chemical composition of treated cellulose samples was evaluated with ATR-FTIR and TGA. Biological activity was evaluated by CL - chemical luminiscence methods.
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