Project information
Exprese proteinů rodiny Myb v adenokarcinomech tlustého střeva a vztah k jejich metastatickému potenciálu
(MYBMET)
- Project Identification
- NT13441-4/2012
- Project Period
- 4/2012 - 12/2015
- Investor / Pogramme / Project type
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Ministry of Health of the CR
- MU Faculty or unit
- Faculty of Science
- Cooperating Organization
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St. Anne's University Hospital Brno
- Responsible person prof. MUDr. Ivan Čapov, CSc.
- Responsible person Prof. MUDr. Markéta Hermanová, Ph.D.
Cílem projektu je vyhodnocení vlivu proteinů c-Myb a B-Myb na metastotický potenciál časných forem nádorů kolorekta.
Publications
Total number of publications: 31
2014
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Plant Coumestans: Recent Advances and Future Perspectives in Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry, year: 2014, volume: 14, edition: 10, DOI
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The regulation of actin cytoskeleton by c-Myb: potential implications for site-specific metastases of breast cancer
Year: 2014, type: Conference abstract
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The role of c-Myb in survival signaling pathways of colorectal carcinoma cells
Year: 2014, type: Conference abstract
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Transendothelial migration in breast cancer metastasis: when does c-Myb step in?
Year: 2014, type: Conference abstract
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Úloha proteinu c-Myb v biologii nádorových buněk kolorekta: nové možnosti boje s nádory rezistentními k chemoterapii?
Year: 2014, type: Conference abstract
2013
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Acidic pH of tumor microenvironment enhances cytotoxicity of disulfiram/Cu2+ complex to breast and colon cancer cells
CHEMOTHERAPY, year: 2013, volume: 2013, edition: 59, DOI
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c-Myb increases resistance of colon carcinoma cells to cisplatin by activation of MAPKp38δ and JNK/c-Jun signaling pathways
Year: 2013, type: Conference abstract
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c-Myb-řízená deregulace MAPK p38 a JNK: potenciální mechanismus rezistence nádorových buněk kolorekta k cytotoxickým agens
Year: 2013, type: Conference abstract
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Funkce proteinu c-Myb ve vybraných aspektech kancerogeneze
Informační listy, year: 2013, volume: 2013, edition: 41
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Is increased resistance of colorectal carcinoma cells to cytotoxic agents caused by the c-Myb-dependent activation of p38MAPK and PI3K/Akt signaling pathways?
Year: 2013, type: Conference abstract