Iowa Gambling Task in patients with early-onset Parkinson's disease: strategy analysis

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Publikace nespadá pod Pedagogickou fakultu, ale pod Středoevropský technologický institut. Oficiální stránka publikace je na webu muni.cz.
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GESCHEIDT Tomáš CZEKÓOVÁ Kristína URBÁNEK Tomáš MAREČEK Radek MIKL Michal KUBÍKOVÁ Radka TELECKÁ Sabina ANDRLOVÁ Hana HUSÁROVÁ Ivica BAREŠ Martin

Rok publikování 2012
Druh Článek v odborném periodiku
Časopis / Zdroj NEUROLOGICAL SCIENCES
Fakulta / Pracoviště MU

Středoevropský technologický institut

Citace
www http://link.springer.com/article/10.1007/s10072-012-1086-x?null
Doi http://dx.doi.org/10.1007/s10072-012-1086-x
Obor Neurologie, neurochirurgie, neurovědy
Klíčová slova Parkinson s disease; Iowa Gambling Task; Decision making; Executive function
Přiložené soubory
Popis The aim of our study was to analyse decision making in early-onset Parkinson's disease (PD) patients performing the Iowa Gambling Task (IGT). We compared 19 patients with early-onset PD (<45 years) on dopaminergic medication (no evidence of depression, dementia, executive dysfunction according to the Tower of London test and the Stroop test, or pathological gambling) with 20 age-matched controls. A computer version of the IGT was employed. The PD patients achieved slightly lower IGT scores than the control group. A detailed analysis based on 'shift frequencies' between the individual decks showed that the patients tended to change their preferences for the decks more frequently, with a higher preference for the 'disadvantageous' deck B. Control subjects seemed to develop a more effective strategy. These differences could be caused by the poorer ability of the patients to develop any strategy at all. We observed changes in decision making during IGT performance in patients with early-onset PD, although they had no executive dysfunction as measured by established neuropsychological tests. The more detailed analysis employed in the present study could lead to a more accurate study of IGT performance and application of IGT in clinical practice.
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