Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors

Varování

Publikace nespadá pod Pedagogickou fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.
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GESCHEIDT Tomáš LOSADA Veronika Ibarburu L. Y. MENŠÍKOVÁ Kateřina DUŠEK Ladislav CZEKÓOVÁ Kristína MENCLOVÁ Petra KAŇOVSKÝ Petr ROTH Jan BAREŠ Martin

Rok publikování 2016
Druh Článek v odborném periodiku
Časopis / Zdroj Basal Ganglia
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1016/j.baga.2016.09.001
Obor Neurologie, neurochirurgie, neurovědy
Klíčová slova Parkinson's disease; Impulse control disorders; Pathological gambling; Dopamine agonists; Personality
Přiložené soubory
Popis Introduction: The aim of this cross-sectional study was to investigate the frequency and factors associated with impulse control disorder (ICD) symptoms, including personality characteristics, in Czech young-onset Parkinson's disease (PD) patients. Subjects and methods: We examined 49 young-onset PD patients and 38 age-matched control subjects. ICD symptoms were identified using the South Oaks Gambling Screen and modified Minnesota Impulse Disorders Interview. Results: A higher prevalence of pathological gambling and hypersexuality was found in PD patients than in control subjects. A higher frequency of pathological gambling in our sample of young-onset PD patients was found in patients using dopamine agonists and in patients with dyskinesias lasting 5 or more years. The frequency of any ICD symptom was associated with coffee consumption, higher reported anxiety, and somatization. ICD symptoms were also related to personality characteristics in PD patients; specifically, patients who manifested any ICD symptom scored significantly higher on Self-assertive/ Antisocial and Reserved/Schizoid personality styles and pathological gambling was associated with lower reported Conscientiousness. Conclusion: Our results demonstrate that ICD presents a real problem in young-onset PD patients. Knowledge about the factors associated with ICD symptoms might be helpful in the proactive search for these pathological behaviours in this specific subgroup of PD patients.
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