Evolutionary Divergence in Hymenoptera and Lepidoptera Telomerase RNAs: A Shift from the Norm in Animal TR Biogenesis
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Rok publikování | 2024 |
Druh | Konferenční abstrakty |
Fakulta / Pracoviště MU | |
Citace | |
Přiložené soubory | |
Popis | Unlike typical animal TRs, which are transcribed by RNA Polymerase II, the TRs in Hymenoptera and Lepidoptera insects display characteristics similar to TRs in plants and ciliates, transcribed by RNA Polymerase III under the control of type 3 promoters. This significant deviation in TR biogenesis challenges the previously assumed monophyletic origin of TRs in animals and suggests an evolutionary shift in TR type and biogenesis within Arthropods. This discovery not only questions the uniformity of TR evolution across animals but also highlights the evolutionary flexibility in telomere biology, particularly in the context of insect genomic stability and telomere maintenance mechanisms. |
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