Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 251
2017
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Acinetobacter colistiniresistens sp nov (formerly genomic species 13 sensu Bouvet and Jeanjean and genomic species 14 sensu Tjernberg and Ursing), isolated from human infections and characterized by intrinsic resistance to polymyxins
International Journal of Systematic and Evolutionary Microbiology, rok: 2017, ročník: 67, vydání: 7, DOI
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AgNi core-shell nanoparticles by hot injection synthesis
Rok: 2017, druh: Konferenční abstrakty
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AgNi nanoalloy prepared by solvothermal hot injection synthesis
Rok: 2017, druh: Konferenční abstrakty
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Bambusuril as a One-Electron Donor for Photoinduced Electron Transfer to Methyl Viologen in Mixed Crystals
Journal of the American Chemical Society, rok: 2017, ročník: 139, vydání: 7, DOI
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BioSAXS practical course 2017
Rok: 2017, druh: Uspořádání workshopu
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CF exkurze talentovaných studentů
Rok: 2017, druh: Popularizační texty
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Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana
Journal of Biological Chemistry, rok: 2017, ročník: 292, vydání: 42, DOI
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COORDINATION COMPOUNDS OF IRON (III), COBALT (II), AND NICKEL (II) WITH (1-AMINO-1-METHYL-ETHYL)PHOSPHONIC ACID AND A NEW SCHIFF BASE LIGAND
Rok: 2017, druh: Konferenční abstrakty
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Cryo-electron Microscopy Study of the Genome Release of the Dicistrovirus Israeli Acute Bee Paralysis Virus
JOURNAL OF VIROLOGY, rok: 2017, ročník: 91, vydání: 4, DOI
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Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions
Nucleic Acids Research, rok: 2017, ročník: 45, vydání: 5, DOI