Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 251
2017
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VUT students from Faculty of chemistry
Rok: 2017, druh: Popularizační texty
2016
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1st single crystal diffraction workshop
Rok: 2016, druh: Uspořádání workshopu
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2 nd BioSAXS hands-on seminar
Rok: 2016, druh: Uspořádání workshopu
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A Cucurbituril Derivative That Exhibits Cation-Modulated Self Assembly
Journal of Organic Chemistry, rok: 2016, ročník: 81, vydání: 14, DOI
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AFM a nanobiotechnologie
Rok: 2016, druh: Uspořádání workshopu
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CIISB Kick-off Meeting
Rok: 2016, druh: Uspořádání konference
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Den otevřených dvěří pro veřejnost
Rok: 2016, druh: Popularizační texty
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Efficient Procedure for N-Glycan Analyses and Detection of Endo H-Like Activity in Human Tumor Specimens
JOURNAL OF PROTEOME RESEARCH, rok: 2016, ročník: 15, vydání: 8, DOI
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Exkurze talentovaných SŠ studentů
Rok: 2016, druh: Popularizační texty
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Methods of biochemical research
Rok: 2016, druh: Uspořádání workshopu