Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 251
2019
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A novel Kunitz protein with proposed dual function from Eudiplozoon nipponicum (Monogenea) impairs haemostasis and action of complement in vitro
International Journal for Parasitology, rok: 2019, ročník: 49, vydání: 5, DOI
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Advanced modes of AFM microscopy: Structural and mechanical characterization of biomolecules and living cells
Rok: 2019, druh: Uspořádání workshopu
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AFM - Raman combined microscope
Rok: 2019, druh: Uspořádání workshopu
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Ag- and Cu-Promoted Mesoporous Ta-SiO2 Catalysts Prepared by Non-Hydrolytic Sol-Gel for the Conversion of Ethanol to Butadiene
CATALYSTS, rok: 2019, ročník: 9, vydání: 11, DOI
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ALUMAZENE REACTIVITY – ADDITION AND SUBSTITUTION REACTIONS ON THE AL3N3 RING
Rok: 2019, druh: Konferenční abstrakty
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Aluminophosphate and -phosphonate Xerogels by Non-Hydrolytic Sol-Gel Reactions
Rok: 2019, druh: Konferenční abstrakty
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Amperometric Immunosensor for Rapid Detection of Honeybee Pathogen Melissococcus Plutonius
Electroanalysis, rok: 2019, ročník: 31, vydání: 10, DOI
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Application of the Enzymatic Electrochemical Biosensors for Monitoring Non-Competitive Inhibition of Enzyme Activity by Heavy Metals
Sensors, rok: 2019, ročník: 19, vydání: 13, DOI
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Atomic Force Microscopy (AFM) for Bio Applications
Rok: 2019, druh: Uspořádání workshopu
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Bambusuril analogs based on alternating glycoluril and xylylene units
Beilstein journal of organic chemistry, rok: 2019, ročník: 15, vydání: June, DOI