Identifikace patogeneticky významných mutací u chronické lymfocytární leukemie pomocí "sekvenování nové generace"

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Title in English Identification of important pathogenetic mutations in chronic lymphocytic leukemia using "next generation sequencing"
Authors

MRÁZ Marek TRBUŠEK Martin DOLEŽALOVÁ Dáša MALČÍKOVÁ Jitka ŠUPÍKOVÁ Jana STAŇO KOZUBÍK Kateřina KANTOROVÁ Barbara MAYER Jiří POSPÍŠILOVÁ Šárka

Year of publication 2012
Type Article in Periodical
Magazine / Source Transfuze a hematologie dnes
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://www.prolekare.cz/transfuze-hematologie-dnes-clanek/identifikace-patogeneticky-vyznamnych-mutaci-u-chronicke-lymfocytarni-leukemie-pomoci-sekvenovani-nove-generace-39136
Field Oncology and hematology
Keywords CLL; SF3B1; NOTCH1; MYD88; next generation sequencing; NGS
Description For a long time, there has been little success in identifying gene mutations responsible for disease onset and progression in chronic lymphocytic leukemia (CLL).
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