Electrochemical analysis of DNA hexamer d(GCGAGC)

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Authors

TŘÍSKOVÁ Iveta TRNKOVÁ Libuše

Year of publication 2016
Type Article in Proceedings
Conference XVI. Workshop of Physical Chemists and Electrochemists
MU Faculty or unit

Faculty of Science

Citation
Field Physical chemistry and theoretical chemistry
Keywords DNA hexamer; mercury electrode; pH effect; concentration effect; hairpin
Description The aim of our research is the voltammetric analysis of the DNA hexameric mini-hairpin d(GCGAGC). The cyclic voltammetric experiment on a hanging mercury drop electrode (HMDE) yields reduction signals of adenine (A) and cytosine (C) moieties and two oxidation signals of guanine moieties (G); these signals were investigated with respect to the hexamer concentration and pH of buffered solutions (phosphate-acetate buffer). Although the character of LSV curves is similar for different concentrations and pHs, the elimination voltammograms are different and show the other character of adsorption.
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