Chromosome 6q deletion correlates with poor prognosis and low relative expression of FOXO3 in chronic lymphocytic leukemia patients

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Authors	JAROŠOVÁ Marie HRUBA M. OLTOVÁ Alexandra PLEVOVÁ Karla KRUZOVA L. KRIEGOVA E. FILLEROVA R. KORIŤÁKOVÁ Eva DOUBEK Michael LYSAK D. PROCHAZKA V. MRÁZ Marek INDRAK K. PAPAJIK T.
Year of publication	2017
Type	Article in Periodical
Magazine / Source	American Journal of Hematology
MU Faculty or unit	Faculty of Medicine
Citation
Doi	http://dx.doi.org/10.1002/ajh.24852
Field	Oncology and hematology
Keywords	Chromosome 6q
Description	Detection of genetic changes has improved the current risk stratification in chronic lymphocytic leukemia (CLL).1,2 Among the known recurrent chromosomal abnormalities,1 6q deletion is less frequent and controversy surrounding its prognostic significance still remains.
Related projects:	Vliv selekce genomických poškození na průběh chronické lymfocytární leukémie Vliv terapeutické inhibice BCR signalizace na genovou expresi u B buněčných malignit a její prognostický a prediktivní význam