Imunohistochemická analýza retrakční kapsy pars tensa ušního bubínku u dětí

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Title in English Immunohistochemical Analysis of Pars Tensa Retraction Pocket in Children
Authors

URÍK Milan HURNÍK P. ŽIAK D. MACHAČ Josef ŠLAPÁK Ivo MOTYKA O. DVOŘÁČKOVÁ J. JABANDŽIEV Petr

Year of publication 2017
Type Article in Periodical
Magazine / Source Otorinolaryngologie a foniatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords retraction pocket; immunohistochemical analysis; cholesteatoma; childhood
Description Introduction: Immunohistochemical analysis of pars tensa retraction pocket in children. Identification of signs typical for cholesteatoma and to support the retraction theory of cholesteatoma. Methods: Standard process of immunohistochemistry of retraction pockets. For immunohistochemistry we used CD45 LCA (Leukocyte common antigen), CD31 (platelet and endothelial cell adhesion molecule), D2-40 (podoplanin - lymphatic vessels) MMP9 (matrix meta-lloproteinase 9 - degradation of extracellular matrix) Ki67 (nuclear proliferation).
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