Structure-functional study of lectins: key players in a fight between host and pathogen

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Authors	HOUSER Josef MALINOVSKÁ Lenka FUJDIAROVÁ Eva JANČAŘÍKOVÁ Gita KOMÁREK Jan HOLKOVÁ Jitka WIMMEROVÁ Michaela
Year of publication	2019
Type	Conference abstract
MU Faculty or unit	Central European Institute of Technology
Citation
Description	Lectins are proteins that reversibly interact with sugars. They role range from glycoprotein folding, through cell maturation to host-pathogen recognition. To describe a lectin we apply a broad range of biophysical techniques. In addition to analysis of its affinity and specificity, we also determine lectin structures and combine our findings with in silico modelling. Our results may find application in basic research, medicine as well as biotechnologies.
Related projects:	Czech Infrastructure for Integrative Structural Biology CEITEC 2020 Czech Infrastructure for Integrative Structural Biology for Human Health