Evaluation of immune response in young patients with sarcoma treated by dendritic cell-based immunotherapy

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Authors

FĚDOROVÁ Lenka ZDRAŽILOVÁ DUBSKÁ Lenka SELINGEROVA I. PILÁTOVÁ Kateřina MÚDRY Peter ŠTĚRBA Jaroslav DEMLOVÁ Regina VALÍK Dalibor

Year of publication 2019
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Individually prepared immunotherapy (ITx) based on autologous dendritic cells (DCs) represents a new possibility in modern advanced anti-cancer treatment. As an extended evaluation of DC-based medicinal product in an academic phase I/II clinical trial for children, adolescents and young adults with progressive, recurrent or primarily metastatic high-risk tumors (EudraCT 2014-003388-39), we performed the examination of T-cell stimulatory properties and detailed peripheral blood immunomonitoring.
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