Method of diagnosis of colorectal cancer

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Authors	SLABÝ Ondřej VYCHYTILOVÁ Petra SVOBODA Marek ŠACHLOVÁ Milana
Year of publication	2020
Type	Patent
MU Faculty or unit	Central European Institute of Technology
Publisher	European Patent Office
State	Germany
Patent's number	EP3431609B1
web	odkaz na stránku Evropského patentového úřadu
Description	The present invention relates to a method of diagnosing and prognosing colorectal cancer using piRNA-hsa-5937, having the sequence TCCCTGGTGGTCTAGTGGTTAGGATTCGGCA (SEQ ID NO. 1), as a biomarker. The biomarker can be combined with other piRNAs or miRNAs. The resulting method uses a body fluid as the input, and therefore is non-invasive, has a high sensitivity and specificity even in very early stages of the disease, and is cost-effective.
Related projects:	Vytvoření diagnostické sady cirkulujících mikroRNA pro neinvazivní časnou diagnostiku a sledování pacientů s kolorektálním karcinomem